National Cancer Institute
National Marrow Donor Program – Glossary
Examples from my Bone Marrow / Stem Cell Transplant Experience
- Stem Cell Transplant
The process of infusing healthy stem cells into persons who have undergone high-dose chemotherapy for one of many forms of leukemia, immunodeficiency, lymphoma, anemias, or metabolic disorders. There are three types of stem cell transplants: autologous, allogeneic and syngeneic. Healthy stem cells are collected from bone marrow, peripheral blood, and umbilical cord blood. Once the healthy stem cells are infused into the patient’s blood stream, the cells move from the blood vessels to the center of the bones, where they begin making new blood cells.
- Collection of Peripheral Blood Stem Cells – Apheresis
A procedure where blood is drawn from a patient’s or donor’s arm and circulated through a machine that removes certain cells such as stem cells, white blood cells or platelets. The rest of the blood is returned to the patient or donor.
- Hematopoietic Stem Cells
Blood forming stem cells capable of producing all the components of blood and marrow. Cells capable of both self-renewal and differentiation to white blood cells, red blood cells, and platelets.
The return of the disease after treatment.